منابع مشابه
A novel design of bioartificial kidneys with improved cell performance and haemocompatibility
Treatment with bioartificial kidneys had beneficial effects in animal experiments and improved survival of critically ill patients with acute kidney injury in a Phase II clinical trial. However, a Phase II b clinical trial failed. This and other results suggested various problems with the current design of bioartificial kidneys. We propose a novel design to improve various properties of device,...
متن کاملCreation of Bioartificial Organs
Regenerative and reparatory medicine is one of the most attractive therapeutic options of the coming years, and the power to replace entire damaged organic structures or organs is, in our opinion, the most innovative possibility in this field. In relation to the creation of bioartificial organs in particular, hearts, lungs, livers, kidneys, ovaries, intestines, pancreas and corneas have already...
متن کاملCurrent status of bioartificial kidney
Current dialysis systems are not perfect considering the low efficacy and cumbersome process of actual practice. To overcome these shortcomings, bioartificial kidneys using renal tubule cells and wearable dialysis are promising ESRD treatments available in the near future. Toward clinical application, however, there are so many obstacles for commercial use of them. In this review, current statu...
متن کاملDesign of a bioartificial pancreas(+).
INTRODUCTION In type 1 diabetes, the β-cells that secrete insulin have been destroyed such that daily exogenous insulin administration is required for the control of blood glucose in individuals with the disease. After the development of reliable techniques for the isolation of islets from the human pancreas, islet transplantation has emerged as a therapeutic option, albeit for only a few selec...
متن کاملThe development of the bioartificial lung.
INTRODUCTION OR BACKGROUND The incidence of chronic lung disease is increasing worldwide due to the spread of risk factors and ageing population. An important advance in treatment would be the development of a bioartificial lung where the blood-gas exchange surface is manufactured from a synthetic or natural scaffold material that is seeded with the appropriate stem or progenitor cells to mimic...
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ژورنال
عنوان ژورنال: Current Stem Cell Reports
سال: 2017
ISSN: 2198-7866
DOI: 10.1007/s40778-017-0079-3